抗生物質Antimycinに関する研究 第三報 : アンチマイシン酸の合成的研究(その3) : 天然アンチマイシン酸の合成

Abstract

In a previous paper it was reported that the synthesis of L or DL-antimycicacid methyl ester methylether was successfully achieved by condensation of nitrosalicylic acid methylether with L or DL-threonine and that the synthetic L-peptide was identical with natural antimycic acid methylester methylether. In this paper N-(3-aminosalicyloyl) L-threonine (natural antimycic acid) has been prepared from 3-aminosalicylic acid benzylether. The synthesis of N-(3-aminosalicyloyl) DL-threonine also has been achieved by the same procedure.